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Understanding Hormonal Health: Key Blood Biomarkers

In the quest for a longer, healthier life, we often look to exercise, nutrition, and mental well-being as primary contributors to our overall health. While these are undeniably important, there’s another critical piece of the puzzle that often gets overlooked—bloodwork and biomarker testing. This powerful tool can unlock insights into your body’s internal health, helping you optimize your lifestyle and prevent chronic illnesses. Here's why regular bloodwork and biomarker monitoring are essential for achieving longevity.

Topic - Diagnostics

22 Sept 2025 • 5 min read

Understanding Hormonal Health: Key Blood Biomarkers
What Are Hormonal Health Biomarkers?
Why Testing These Hormonal Biomarkers Matters
Take Control of Your Hormonal Health

Understanding Hormonal Health: Key Blood Biomarkers

Hormones are essential to the regulation of various bodily functions, including metabolism, mood, reproductive health, and muscle function. When these vital substances fall out of balance, it can lead to a variety of health issues. Fortunately, testing key hormonal biomarkers can provide a clearer picture of your hormonal health and help you take proactive steps to optimize your well-being.

What Are Hormonal Health Biomarkers?

Hormonal health biomarkers are substances found in the blood that reflect the state of your endocrine system. By testing these markers, you can evaluate adrenal, thyroid, and reproductive functions, among others. Regular testing is vital for understanding how well your body is balancing hormones and identifying potential imbalances early on.

Key Blood Biomarkers for Hormonal Health

Cortisol - Total/AM: Cortisol is the primary stress hormone. Measuring cortisol levels helps assess adrenal function and how your body responds to stress. Chronic high levels can indicate adrenal fatigue or stress-related disorders.
Estradiol: A key estrogen hormone that plays an important role in reproductive health, menstrual cycles, and bone health. Imbalances can affect fertility, mood, and overall health.
DHEA-S: DHEA-S is a precursor to both estrogen and testosterone, produced by the adrenal glands. It reflects adrenal function and can provide insights into hormonal balance and age-related decline.
Testosterone Total: This test measures the total amount of testosterone in the body. Testosterone is important for sexual health, muscle mass, bone density, and overall vitality.
Free Testosterone: The unbound form of testosterone that directly affects sexual health, mood, and muscle development. Free testosterone is the active form available for use in the body.
PSA (Prostate-Specific Antigen): PSA is a protein produced by the prostate. Elevated levels may indicate prostate issues, such as benign enlargement or cancer risk.
TSH (Thyroid Stimulating Hormone): TSH regulates thyroid function, which controls metabolism. Abnormal TSH levels can indicate thyroid dysfunction, affecting energy, weight, and mood.
Free T4: The inactive form of thyroid hormone, which is converted into active Free T3 to regulate metabolism. Low levels of Free T4 may suggest hypothyroidism or thyroid dysfunction.
Free T3: The active thyroid hormone responsible for regulating metabolism and energy levels. Low levels can cause fatigue and weight gain, while high levels may result in irritability and weight loss.
FSH (Follicle Stimulating Hormone): Essential for reproductive health, FSH stimulates the production of eggs in women and sperm in men. It is tested to assess ovarian or testicular function and fertility issues.
LH (Luteinizing Hormone): Works with FSH to regulate the reproductive system. It plays a key role in ovulation in women and testosterone production in men.
Sex Hormone Binding Globulin (SHBG): SHBG binds to sex hormones like estrogen and testosterone, controlling their availability. Low levels may lead to excess free testosterone, while high levels can reduce the bioavailability of both testosterone and estrogen.
Progesterone: Regulates the menstrual cycle and supports pregnancy. Low levels can cause irregular cycles, infertility, or complications in pregnancy.
IGF-1 (Insulin-like Growth Factor 1): Produced in response to growth hormone, IGF-1 plays a role in growth, tissue repair, and metabolism. Low levels can indicate growth hormone deficiency or other metabolic issues.
% Testosterone Bioavailable: This measure determines the percentage of testosterone available for use in the body, providing insight into testosterone’s impact on sexual health, muscle function, and mood.
Testosterone Bioavailable: This test measures the testosterone that is free and readily available for use by the body, crucial for sexual health and physical performance.
Prolactin: Involved in milk production in women, prolactin also plays a role in fertility and menstrual cycles. Abnormal prolactin levels may indicate pituitary disorders or thyroid imbalances.
Cortisol : DHEA-S Ratio: The balance between cortisol and DHEA-S offers insights into adrenal health and stress response. An imbalance may indicate adrenal fatigue or dysregulation.

Why Testing These Hormonal Biomarkers Matters

Hormones play a foundational role in health, affecting everything from metabolism and mood to reproduction and stress regulation. Testing these biomarkers helps identify imbalances that may lead to a variety of health issues. Regular testing is essential for tracking hormonal health and taking proactive steps to achieve optimal well-being.

Take Control of Your Hormonal Health

If you’re interested in testing these important hormonal biomarkers, join Geviti today. We’ll test for all of these markers and 70+ others as part of your membership, giving you a comprehensive view of your hormonal health. Let us help you achieve a balanced hormonal profile and optimize your overall well-being.

Disclaimer: The content provided here is intended solely for educational and entertainment purposes. It should not be considered as a substitute for professional advice, diagnosis, or treatment. If you are seeking specific information or guidance on the topic discussed, it is strongly recommended that you consult with a qualified healthcare professional or your doctor to address your individual needs and circumstances.